Current Publications

2017 Publications


Mingnan Chen:

  • An Albumin Binding Polypeptide both Targets Cytotoxic T Lymphocyte Vaccines to Lymph Nodes and Boosts Vaccine Presentation by Dendritic Cells. Theranostics Theranostics. 2018; 8(1): 223–236.
  • Here is a news report for this paper. https://uofuhealth.utah.edu/research-roundup/2017/12/vaccine.php
  • Direct Loading of iTEP-Delivered CTL Epitope onto MHC Class I Complexes on the Dendritic Cell Surface. Mol. Pharmaceutics. Pharmaceutics, 201714(10), pp 3312–3321.
  • An anti-programmed death-1 antibody (aPD-1) fusion protein that self-assembles into a multivalent and functional aPD-1 nanoparticle. Molecular Pharmaceutics. Mol. Pharmaceutics, 2017 14 (5), pp 1494-1500
  • Engineering a self-adjuvanted, iTEP-delivered CTL vaccine. Acta Pharmacologica Sinica. 2017 38: 914–923.

David Grainger:

  • Z. Meidell, R. Robinson, A.V. de Abreu, A.J. Gormley, H. Ghandehari, D.W. Grainger,R. Campbell, “RGDfK-functionalized gold nanorods bind only to activated platelets,” J. Biomed. Mater. Res., A.2017 Jan;105(1):209-217; doi: 10.1002/jbm.a.35902; PMID: 27648522.
  • Diekjürgen, D.W. Grainger, “Polysaccharide matrices used in 3D in vitro cell culture systems, Biomaterials, (2017) 141, 96-115; DOI:0142-9612, https://doi.org/10.1016/j.biomaterials.2017.06.020.
  • L. Falconer, D.W. Grainger, “In Vivo Evaluation of Silver Nanoparticle and Silver Ion Transport after Intranasal Delivery in Mice,” J. Controlled Rel., 269, 1-9.2017.

Hamid Ghandehari:

  • Mohammadpour, S. Safarian*, B. Buckway, H. Ghandehari*, Comparative Endocytosis Mechanisms and Anticancer Effect of HPMA Copolymer- and PAMAM Dendrimer-MTCP Conjugates for Photodynamic Therapy, Macromolecular Biosciences. 2017 Apr;17(4), 2016 Oct 25 [Epub ahead of print]. *Corresponding Coauthors
  • Frazier, A. Payne, C. Dillon, N. Subrahmanyam, H. Ghandehari H, Enhanced Efficacy of Combination Heat Shock Targeted Polymer Therapeutics with High Intensity Focused Ultrasound, Nanomedicine, 13:1235-1243 (2017).
  • Zeller Meidell, R. Robinson, A. Vieira-de-Abreu, A.J. Gormley, H. Ghandehari, D.W. Grainger, R. Campbell, RGDfK-Functionalized Gold Nanorods Bind only to Activated Platelets, Journal of Biomedical Materials Research, 105:209-217 (2017).
  • J. Anchordoquy, Y. Barenholz, D. Boraschi, M. Chorny, P. Decuzzi, M.A. Dobrovolskaia, Z.S. Farhangrazi, D. Farrell, A. Gabizon, H. Ghandehari, B. Godin, N.M. La-Beck, J. Ljubimova, S.M. Moghimi, L. Pagliaro, J.H. Park, D. Peer, E. Ruoslahti, N.J. Serkova, D. Simberg, Mechanisms and Barriers in Cancer Nanomedicine: Addressing Challenges, Looking for Solutions, ACS Nano, 11:12-18 (2017).
  • J. Isaacson, M.M. Jensen, N.B. Subrahmanyam, H. Ghandehari, Matrix-Metalloproteinases as Targets for Controlled Delivery in Cancer: An Analysis of Upregulation and Expression, Journal of Controlled Release, Journal of Controlled Release, 259:62-75 (2017).
  • M. Jensen, W. Jia, K.J. Isaacson, A. Schults, J. Cappello, G.D. Prestwich, S. Oottamasathien*, H. Ghandehari*Silk-Elastinlike Protein Polymers Enhance the Efficacy of a Therapeutic Glycosaminoglycan for Prophylactic Treatment of Radiation-Induced Proctitis, Journal of Controlled Release, 263:46-56 (2017). *Corresponding Coauthors.
  • Ghandehari, ADDR Editors’ Collection. Advanced Drug Delivery Reviews, 108: 1 (2017).
  • P. Hadipour Moghaddam, J. Saikia, M. Yazdimamaghani, H. Ghandehari, Redox-Responsive Polysulfide-Based Biodegradable Organosilica Nanoparticles for Delivery of Bioactive Agents, ACS Applied Materials and Interfaces, 9:21133-21146 (2017).
  • J. Isaacson, M.M. Jensen, A.H. Watanabe, B.E. Green, M.A. Correa, J. Cappello, H. Ghandehari. Self-Assembly of Thermoresponsive Recombinant Silk-Elastinlike Nanogels. Macromolecular Biosciences. 2017 Sep 4 [Epub ahead of print].
  • Yazdimamaghani, P.J. Moos*, and H. Ghandehari*. Global Gene Expression Analysis of Macrophage Response Induced by Nonporous and Porous Silica Nanoparticles, Nanomedicine. 2017 Dec 5 [E pub ahead of print]. *Corresponding Coauthors.
  • Ghandehari, ADDR Editors’ Collection. Advanced Drug Delivery Reviews, 122: 1 (2017).

Sung Wan Kim:

  • Optimized Biodegradable Polymeric Reservoir-mediated Local and Sustained Co-delivery of Dendritic Dells and Oncolytic Adenovirus Co-expressing IL-12 and GM-CSF for Cancer Immunotherapy, E. Oh, J-E. Oh, J.W. Hong, Y.H. Chung, Y. Lee, K. D. Park, S.W. Kim, C-O. Yun, Journal of Controlled Release, 259:115-127 (2017).
  • Synergistic Antitumor Effect Mediated by a Paclitaxel-conjugated Polymeric Micelle-coated oncolytic Adenovirus, D. Kasala, S-H. Lee, JW. Hong, J-W. Choi, K. Nam, YH. Chung, SW. Kim, and C-O. Yun, Biomaterials, 145:207-232 (2017).
  • Factorial Design Based Multivariate Modeling and Optimization of Tunable Bioresponsive Arginine Grafted Poly(cystaminebis(acrylamide)-diaminohexane) Polymeric Matrix Based Nanocarriers, R. Yang, K. Nam, SW. Kim, J. Turkson, Y. Zou, Y.Y. Zou, R. Haware, and M.B.Chougule. Molecular Pharmaceutics, 14:252-263 (2017).

Jindrich Kopecek:

  • Zhang, J. Yang, D.C. Radford, Y. Fang, J. Kopeček, FRET Imaging of Enzyme-Responsive HPMA Copolymer Conjugate. Macromol. Biosci. 17, 1600125 (2017). doi: 10.1002/mabi.201600125.
  • Pelaz, C. Alexiou, R. Alvarez-Puebla, F. Alves, A. Andrews, S. Ashraf, L. Balogh, L. Ballerini, A. Bestetti, C. Brendel, S. Bossi, M. Carril, W. Chan, C. Chen, X. Chen, S. Shen, Z. Cheng, D. Cui, J. Du, C. Dullin, A. Escudero, N. Feliu, M. Gao, M. George, A. Grünweller, Z. Gu, Y. Gogotsi, N. Halas, N. Hampp, R. Hartmann, M. Hersam, P. Hunziker, J. Ji, X. Jiang, P. Jungebluth, P. Kadhiresan, K. Kataoka, A. Khademhosseini, J. Kopeček, N. Kotov, H. Krug, D.S. Lee, C.-M. Lehr, K.W. Leong, X.-J. Liang, M.L. Ling, L. Liz-Marzán, X. Ma, P. Macchiarini, H. Meng, H. Möhwald, P. Mulvaney, A. Nél, S. Nie, P. Nordlander, T. Okano, J. Oliviera, T.H. Park, R. Penner, M. Prato, V. Puntes, V. Rotello, A. Samarakoon, R. Schaak, Y. Shen, S. Sjoqvist, A.G. Skirtach, M. Sollman, M. Stevens, B.Z. Tang, R. Tietze, B. Udugama, H.-W. Sung, T. Weil, P. Weiss, I. Willner, Y. Wu, L. Yang, Z. Yue, Q. Zhang, Q. Zhang, X. Zhang, Y. Zhao, X. Zhou, W. Parak, Diverse Applications of Nanomedicine. ACS Nano11, 2313-2381 (2017).
  • A. Low, C.V. Galliford, Y.L. Jones-Hall, J. Roy, J. Yang, P.S. Low, J. Kopeček, Healing Efficacy of Fracture-Targeted GSK3bInhibitor-Loaded Micelles for Improved Fracture Repair. Nanomedicine (Lond.)12, 185-193 (2017).
  • Yang, R. Zhang, H. Pan, Y. Li, Y. Fang, L. Zhang, J. Kopeček, Backbone Degradable HPMA Copolymer Conjugates with Gemcitabine and Paclitaxel: Impact of Molecular Weight on Activity toward Human Ovarian Carcinoma Xenografts. Mol. Pharmaceutics14, 1384-1394 (2017).
  • Zhang, Y. Fang, J. Yang, J. Kopeček, Drug-Free Macromolecular Therapeutics: Impact of Structure on Induction of Apoptosis in Raji B Cells. J. Controlled Release263, 139-150 (2017).
  • Zhang, Y. Fang, J. Kopeček, J. Yang, A New Construct of Antibody-Drug Conjugates for Treatment of Non-Hodgkin’s Lymphoma. Eur. J. Pharm. Sci. 103, 36-46 (2017).
  • Yang, J. Kopeček, The Light at the End of the Tunnel – Second Generation HPMA Conjugates for Cancer Treatment. Curr. Opin. Colloid Interface Sci. 31, 30-42 (2017).
  • Li, J. Yang, J. Wang, J. Kopeček, Drug-Free Macromolecular Therapeutics Induce Apoptosis via Calcium Influx and Mitochondrial Signaling Pathway. Macromol. Biosci. (2017) doi: 10.1002/mabi.201700196.
  • Highlighted in Advanced Science News http://www.advancedsciencenews.com/molecular-therapeutics-drug-free-cancer-treatment/November 12, 2017
  • Zhang, Y. Fang, J. Yang, D.C. Radford, J. Kopeček, Human Serum Albumin Based Drug-Free Macromolecular Therapeutics: Apoptosis Induction by Coiled-Coil-Mediated Cross-Linking of CD20 Antigens on Lymphoma B Cell Surface.ACS Macro Letters, submitted.

John Mauger:

  • Mauger, J. Physicochemical Properties of Buffers Used in Simulated Biological Fluids with Potential Application for In Vitro Dissolution Testing: A Mini-review. Dissolution Technologies 2017, 24(3), 38-51.  dx.doi.org/10.14227/DT240317P38.

Shawn Owen:

  • A Dixon, S Kim, B Baumgartner, S Krippner, S Owen. A Tri-part Protein Complementation System Using Antibody-Small Peptide Fusions Enables Homogeneous Immunoassays. Scientific Reports 7 (1), 8186



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