Marco Bortolato

 

Marco Bortolato

Title:

Associate Professor


Email:

marco.bortolato@utah.edu



Education:

 

M.D. 2000, University of Cagliari, Italy

Ph.D. 2004, Pharmacology, University of Cagliari, Italy

Specialization in Neurology 2009, University of Cagliari, Italy




 

Research Interests

 

My research is primarily focused on the characterization of the biological bases of neurodevelopmental disorders through the employment of behavioral tests in animal models. In particular, my key scientific interest is the identification of the mechanisms of interaction between lipid mediators (including neuroactive steroids and endocannabinoids) and key brain neurotransmitters, such as dopamine and serotonin. To this end, we employ a broad array of behavioral, biochemical and molecular biological techniques, as well as stereotactic surgery and HPLC.

The long-term goal of this research is the development of novel therapeutic agents for the treatment of pathological aggression, autism-spectrum disorder, Tourette syndrome, schizophrenia and impulse-control disorders (such as pathological gambling).

My laboratory is currently involved in two major translational research projects. The first target of our investigations is the characterization of the molecular substrates of gene x environment interactions in impulsive aggression. The second aim of our research is the development of novel steroid- and cannabinoid-based tools for the therapy of impulse-control disorders, Tourette syndrome, autism and schizophrenia. Both projects involve multiple collaborations with several basic and clinical scientists in US, Canada, Italy, France and Germany.




 

Selected Publications

 

To veiw Dr. Marco Bortolato's publications, please visit his PubMed page:
http://goo.gl/kSHBTd

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