Daniel M. Witt, PharmD, FCCP, BCPS

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Title:
Professor and Chair, Assistant Dean of Clinical Affairs

Contact

Office: L. S. Skaggs Pharmacy Institute, Room 4323
Phone: (801) 581-8851
Fax: (801) 587-7923
Email: Dan.Witt@pharm.utah.edu

Education

  • Advanced Residency in Primary Care and Family Medicine, University of Washington, Seattle, Washington. July 1992-June 1993.
  • Clinical Pharmacy Residency, University of Washington and Harborview Medical Centers, Seattle, Washington. July 1990-June 1992.
  • University of Washington, Seattle, Washington. Doctor of Pharmacy. May 1992.
  • University of Utah, Salt Lake City, Utah. Bachelor of Science in Pharmacy. May 1990.
  • Snow College, Ephraim, Utah. Associate of Science. December 1984.

Research Interest

Principal areas of research interest are: 1) documentation of the clinical and economic impact of clinical pharmacy services; 2) providing optimized management of anticoagulation therapy; and 3) providing practical evidence-based solutions to front-line anticoagulation providers.

Selected Publications

  • Lousberg TR, Witt DM, Beall DG, Carter BL, Malone D. Evaluation of excessive anticoagulation in a group model health maintenance organization. Archives of Internal Medicine 1998;158:528-534
  • Witt DM, Humphries TL. A retrospective evaluation of the management of excessive anticoagulation in an established clinical pharmacy anticoagulation service compared to traditional care. Journal of Thrombosis and Thrombolysis 2003;15:113-118
  • Witt DM, Sadler MA, Shanahan R, Mazzoli G, Tillman TJ. Effect of a centralized clinical pharmacy anticoagulation service on the outcomes of anticoagulation therapy. CHEST 2005;127:1515-1522
  • Garcia DA, Witt DM, Hylek E, Wittkowsky AK, Nutescu EA, Jacobson A, Moll S, Merli GJ, Crowther M, Earl L, Becker RC, Oertel L, Jaffer A, Ansell JE. Delivery of optimized anticoagulant therapy: consensus statement from the Anticoagulation Forum. Annals of Pharmacotherapy 2008;42:979-988
  • Witt DM, Delate T, Clark NP, Martell C, Tran T, Crowther MA, Garcia DA, Ageno W, Hylek EM, on behalf of the WARPED Consortium. Outcomes and predictors of very stable INR control during chronic anticoagulation therapy. Blood 2009;114:952-956
  • Witt DM, Delate T, McCool KH, Dowd MB, Clark NP, Crowther MA, Garcia DA, Ageno W, Dentali F, Hylek EM, Rector WG, on behalf of the WARPED Consortium. Incidence and predictors of bleeding or thrombosis after polypectomy in patients receiving and not receiving anticoagulation therapy. Journal of Thrombosis and Haemostasis 2009;7:1982-9
  • Holbrook A, Schulman S, Witt DM, Vandvik PO, Fish J, Kovaks MJ, Svensson PJ, Veenstra DL, Crowther M, Guyatt GH. Evidence-based management of anticoagulant therapy: Antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians evidence-based clinical practice guidelines. CHEST 2012;141 (2 suppl):e152S-e184S.
  • Witt DM, Delate T, Garcia DA, Clark NP, Hylek EM, Ageno W, Dentali F, Crowther MA. Risk of thromboembolism, recurrent hemorrhage, and death after warfarin therapy interruption for gastrointestinal tract bleeding. Archives of Internal Medicine 2012;172:1484-1491
  • Witt DM, Delate T, Clark NP, Garcia DA, Hylek EM, Ageno W, Dentali F, Crowther MA. Nonadherence with INR monitoring and anticoagulant complications. Thrombosis Research 2013;132:e124-e130
  • Clark NP, Witt DM, Davies LE, Saito EM, McCool KH, Douketis JD, Metz KR, Delate T. Bleeding, recurrent venous thromboembolism, and mortality risks during warfarin interruption for invasive procedures. JAMA Internal Medicine 2015;175:1163-1168
  • Witt DM, Delate T, Hylek EM, Clark NP, Crowther MA, Dentali F, Ageno W, Martinez KD, Garcia DA. Effect of warfarin on intracranial hemorrhage incidence and fatal outcomes. Thrombosis Research 2013;132:770-775
  • Witt DM, Clark NP, Martinez K, Schroeder A, Garcia D, Crowther MA, Ageno W, Dentali F, Ye X, Hylek E, Delate T. Risk of thromboembolism, recurrent hemorrhage, and death after warfarin therapy interruption for intracranial hemorrhage. Thrombosis Research 2015;136:1040-1044.
  • Witt DM, Clark NP, Kaatz S, Schnurr T, Ansell JE. Guidance for the practical management of warfarin therapy in the treatment of venous thromboembolism. Journal of Thrombosis and Thrombolysis 2016;41:187-205

Book Chapters

  • Witt DM, Ellsworth AJ. Common infections in ambulatory care practice: part I. In: Carter BL, Lake KD, Raebel MA, Bertch KE, Israel MK, Jermain DM, et al., eds. Pharmacotherapy Self-Assessment Program, 3rd ed. Kansas City: ACCP, 1998:25-72
  • Witt DM, Tillman DJ. Thrombosis. In: Bertch K, Dunsworth T, Fagan S, Hayney M, Mueller B, O’Donnell D, et al. eds. Pharmacotherapy Self-Assessment Program, 4th ed. Kansas City: ACCP:85-122
  • Haines ST, Zeolla M, Witt DM. Venous Thromboembolism. In: DiPiro JT, Talbert RL, Yee GC, Matzke GR, Wells BG, Posey LM, eds. Pharmacotherapy: A Pathophysiologic Approach, 6th ed. McGraw-Hill Medical
  • Haines ST, Witt DM, Nutescu E. Venous Thromboembolism. In: DiPiro JT, Talbert RL, Yee GC, Matzke GR, Wells BG, Posey LM, eds. Pharmacotherapy: A Pathophysiologic Approach, 7th ed. McGraw-Hill Medical
  • Witt DM. Improving the Quality of Anticoagulation Therapy Management. In: Ansell JE, Oertel LB, Wittkowsky AK, eds. Managing Oral Anticoagulation Therapy: Clinical and Operational Guidelines, 3rd ed. Wolters Kluwer/Facts & Comparisons
  • Witt DM, Haines ST, Nutescu E. Venous Thromboembolism. In: DiPiro JT, Talbert RL, Yee GC, Matzke GR, Wells BG, Posey LM, eds. Pharmacotherapy: A Pathophysiologic Approach, 8th ed. McGraw-Hill Medical
  • Witt DM. Atrial fibrillation. In: Dager WE, Gulseth MP, Nutescu EA, eds. Anticoagulation Therapy: A Point of Care Guide. American Society of Health-System Pharmacists
  • McCool KH, Witt DM. Pharmacology of Parenteral Anticoagulants. In: Fang MC, ed. Inpatient Anticoagulation, 1st ed. Wiley-Blackwell
  • Witt DM, Clark NP. Anticoagulant Drugs: Current and Novel. In: Ferro A, Garcia D, eds. Antiplatelet and Anticoagulation Therapy. Springer
  • Witt DM, Clark NP. Venous Thromboembolism. In: DiPiro JT, Talbert RL, Yee GC, Matzke GR, Wells BG, Posey LM, eds. Pharmacotherapy: A Pathophysiologic Approach, 9th ed. McGraw-Hill Medical
  • Witt DM, Clark NP, Vazquez S. Venous Thromboembolism. In: DiPiro JT, Talbert RL, Yee GC, Matzke GR, Wells BG, Posey LM, eds. Pharmacotherapy: A Pathophysiologic Approach, 10th ed. McGraw-Hill Medical
  • Witt DM. In Kiser K, ed. Patient Presenting with Minor Bleeding. Oral Anticoagulation Therapy: Cases and Clinical Correlation. Springer
  • Witt DM. In Kiser K, ed. Patient Presenting with Major, Life-Threatening Bleeding. Oral Anticoagulation Therapy: Cases and Clinical Correlation. Springer

Positions Held

  • Chair and Professor (Clinical), University of Utah College of Pharmacy Department of Pharmacotherapy, Salt Lake City, Utah. 2017-present
  • Vice Chair and Professor (Clinical); Assistant Dean for Clinical Affairs, University of Utah College of Pharmacy Department of Pharmacotherapy, Salt Lake City, Utah. 2014-2017.
  • Senior Manager, Clinical Pharmacy Research and Applied Pharmacogenomics, Kaiser Permanente, Aurora, Colorado. 2010-2014.
  • Senior Manager, Clinical Pharmacy Services and Research, Kaiser Permanente Colorado, Aurora,. 2009-2010.
  • Manager, Clinical Pharmacy Services, Kaiser Permanente, Aurora, Colorado. 2004-2009.
  • Chief, Clinical Pharmacy Service, Kaiser Permanente, Westminster, Colorado. 2001-2004
  • Supervisor, Clinical Pharmacy Anticoagulation Service, Kaiser Permanente, Westminster, Colorado. 1997-2001.
  • Clinical Pharmacy Specialist, Internal Medicine, Kaiser Permanente, Westminster, Colorado. 1993-1997

Professional Affliations

  • American Society of Health-Systems Pharmacy
  • American College of Clinical Pharmacy (Fellow 2004)
  • Anticoagulation Forum (Board of Directors)
  • International Society on Thrombosis and Haemostasis

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