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james-herron

James Herron, Ph.D.

Academic Information

Departments Director of Graduate Studies - College of Pharmacy , Associate Professor - Molecular Pharmaceutics

Academic Office Information

james.herron@utah.edu

801-581-7303

Research Interests

  • Optical biosensor applications in biodefense, diagnostics, companion diagnostics, environmental and food testing, and personalized medicine
  • High-throughput homogeneous fluorescence assays for use in biodefense, diagnostics, and quality control and assurance
  • Dynamic light scattering as a means of detecting intravenous (IV) drug incompatibilities, when co-administered through the same IV line

RESEARCH INTERESTS

Dr. Herron is interested in translational research – specifically, translating innovative near-patient diagnostics technologies from the laboratory into the clinic. Presently, his research is focused in three areas: 

1) optical biosensor applications in biodefense, diagnostics, companion diagnostics, environmental and food testing, and personalized medicine; 

2) high-throughput homogeneous fluorescence assays for use in biodefense, diagnostics, and quality control and assurance; and 

3) dynamic light scattering as a means of detecting intravenous (IV) drug incompatibilities, when co-administered through the same IV line. He has published 113 full-length research articles and 107 abstracts. 

He also edited a book entitled “Physical Methods to Characterize Pharmaceutical Proteins.” 

Dr. Herron has 32 US and 41 foreign patents and has co-founded three different point-of-care diagnostics companies to commercialize biosensor technology developed in his laboratory. He has also consulted for 3M Corporation, Abbott Laboratories, Agri-Analysis, ARUP Laboratories, Echelon Biosciences, Johnson & Johnson, Kansas Technology Enterprise Corporation, and mBio Diagnostics. He also chaired the translational development subcommittee of the Rocky Mountain Regional Center of Excellence in Biodefense and Emerging Infectious Disease (RMRCE), a NIH-sponsored center that supports basic and translational research in biodefense and infectious disease, with focus on developing countermeasures for both.

RELATED LINKS

FAR Webpage

College of Pharmacy

Education History

Undergraduate University of Illinois Urbana-Champaign
BS, Biology
Graduate Training University of Illinois, Urbana-Champaign
MS, Microbiology
Doctoral Training University of Illinois Urbana-Champaign
PhD, Microbiology

Selected Publications

Journal Article

  1. Probing bis-ANS binding sites of different affinity on aggregated IgG by steady-state fluorescence, time-resolved fluorescence and isothermal titration calorimetry. Hawe A, Rispens T, Herron JN, Jiskoot W. J Pharm Sci. 2011 Apr;100(4):1294-305. doi: 10.1002/jps.22368. Epub 2010 Oct 18. PMID: 20957745

  2. Analytical approaches to the study of monoclonal antibody stability. Jiskoot W, Beuvery EC, de Koning AA, Herron JN, Crommelin DJ. Pharm Res. 1990 Dec;7(12):1234-41. doi: 10.1023/a:1015925519154. PMID: 2095560

  3. Fluorescent probe studies of the interactions of 1-alkyl-2-pyrrolidones with stratum corneum lipid liposomes. Yoneto K, Li SK, Higuchi WI, Jiskoot W, Herron JN. J Pharm Sci. 1996 May;85(5):511-7. doi: 10.1021/js950471x. PMID: 8742943

    More Selected Publications