RESEARCH INTERESTS
Dr. Herron is interested in translational research – specifically, translating innovative near-patient diagnostics technologies from the laboratory into the clinic. Presently, his research is focused in three areas:
1) optical biosensor applications in biodefense, diagnostics, companion diagnostics, environmental and food testing, and personalized medicine;
2) high-throughput homogeneous fluorescence assays for use in biodefense, diagnostics, and quality control and assurance; and
3) dynamic light scattering as a means of detecting intravenous (IV) drug incompatibilities, when co-administered through the same IV line. He has published 113 full-length research articles and 107 abstracts.
He also edited a book entitled “Physical Methods to Characterize Pharmaceutical Proteins.”
Dr. Herron has 32 US and 41 foreign patents and has co-founded three different point-of-care diagnostics companies to commercialize biosensor technology developed in his laboratory. He has also consulted for 3M Corporation, Abbott Laboratories, Agri-Analysis, ARUP Laboratories, Echelon Biosciences, Johnson & Johnson, Kansas Technology Enterprise Corporation, and mBio Diagnostics. He also chaired the translational development subcommittee of the Rocky Mountain Regional Center of Excellence in Biodefense and Emerging Infectious Disease (RMRCE), a NIH-sponsored center that supports basic and translational research in biodefense and infectious disease, with focus on developing countermeasures for both.
RELATED LINKS
Education History
Undergraduate |
University of Illinois Urbana-Champaign |
BS, Biology |
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Graduate Training |
University of Illinois, Urbana-Champaign |
MS, Microbiology |
University of Illinois Urbana-Champaign |
PhD, Microbiology |
Selected Publications
Journal Article
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Probing bis-ANS binding sites of different affinity on aggregated IgG by steady-state fluorescence, time-resolved fluorescence and isothermal titration calorimetry. Hawe A, Rispens T, Herron JN, Jiskoot W. J Pharm Sci. 2011 Apr;100(4):1294-305. doi: 10.1002/jps.22368. Epub 2010 Oct 18. PMID: 20957745
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Analytical approaches to the study of monoclonal antibody stability. Jiskoot W, Beuvery EC, de Koning AA, Herron JN, Crommelin DJ. Pharm Res. 1990 Dec;7(12):1234-41. doi: 10.1023/a:1015925519154. PMID: 2095560
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Fluorescent probe studies of the interactions of 1-alkyl-2-pyrrolidones with stratum corneum lipid liposomes. Yoneto K, Li SK, Higuchi WI, Jiskoot W, Herron JN. J Pharm Sci. 1996 May;85(5):511-7. doi: 10.1021/js950471x. PMID: 8742943