The project uses animal seizure models and neuroscience techniques to help develop new antiepileptic agents. Some 800-1000 novel compounds per year are evaluated against conventional drugs for anticonvulsant efficacy and potency, neurotoxicity, effect on liver function, and mechanism of action. Promising compounds, which exhibit a high level and/or unusual spectrum of anticonvulsant activity with superior therapeutic potential, are selected for detailed toxicology studies and subsequent clinical trials in epileptic patients. The project has been continually funded since 1975 and every new anticonvulsant introduced to clinical use in the USA during the past 40 years has been evaluated in this research program.
The program is an integral part of the Department of Pharmacology and Toxicology and, as such, provides a site for research training of undergraduate students, departmental graduate students and postdoctoral fellows. Faculty aligned with the program also provide instruction to professional students in the College of Pharmacy and the School of Medicine.
The Utah Poison Control Center (UPCC) will join poison centers and poison prevention partners across the country in celebrating the 56th annual National Poison Prevention Week (NPPW), March 18-24, 2018, a week dedicated to raising awareness about poisoning and highlighting ways to prevent it.... Read More
Legislators approved the supplemental appropriations request for the Utah Poison Control Center... Read More
Congratulations to You Han Bae for being appointed as a Distinguished Professor of Pharmaceutics and Pharmaceutical Chemistry... Read More
Managing Chronic Pain during the Opioid Crisis: Add a Pharmacist to the Care Team... Read More
University of Utah Health Receives Nearly $10 Million to Identify Natural, Non-opioid Compounds to Manage Pain.... Read More
Psychiatry
Professor Jindrich Kopecek has been named the winner of the T. & A. Higuchi Memorial Lectureship Award 2018... Read More
