Sustainable regenerative medicine for joint cartilage injury being developed
Dr. Makoto Kondo and Dr. Teruo Okano have been developing a “sustainable” regenerative medicine for joint cartilage injury using donor juvenile cartilage source with interdisciplinary collaboration with Department of Orthopaedics, University of Utah and Department of Orthopaedics, Tokai University, Japan. In contrast to order-made autologous cell therapy, their allogeneic cell sheet technology is a promising solution for treating a number of patients with lower cost. Their results show safety of the engineered cell sheets, and demonstrate native-like hyaline cartilage regeneration by the implanted human cell sheet in their animal xenograft model. This research has resulted in a reputable npj Regenerative Medicine. DOI:10.1038/s41536-021-00173-9
