Interdisciplinary project receives funding to improve ECMO life support
The project “Micellar encapsulation of hydrophobic drugs to prevent their adsorption on extracorporeal membrane oxygenation (ECMO) circuits and to increase drug bioavailability” was recently funded by the Utah Clinical and Translational Science Institute, Center for Clinical and Translation Science. This interdisciplinary project is a collaboration between Drs. Kevin Watt and Venkata Yellepeddi in Pediatrics and Hamid Ghandehari and Nitish Khurana in Pharmaceutics. The research will focus on formulating poloxamer based micelles encapsulating propofol to prevent adsorption to ECMO circuits, which is currently a significant clinical challenge for critically ill patients on ECMO life support.