CSTEC@Utah Publication in International Journal of Molecular Sciences
Congratulations to the Cell Sheet Tissue Engineering Center in the Department of Molecular Pharmaceutics (CSTEC@Utah) on their recent publication! “Engineered Bone Marrow Stem Cell-Sheets Alleviate Renal Damage in a Rat Chronic Glomerulonephritis Model” was published in the International Journal of Molecular Sciences in February 2023.
CSTEC@Utah developed mesenchymal stem cell (MSC) sheets retaining intrinsic cell adhesion proteins, which promotes transplantation efficacy to target tissue for kidney regeneration. The MSC sheets facilitated MSC transplantation and function, and effectively retarded progressive renal fibrosis via paracrine actions on anti-cellular inflammation, oxidative stress, and apoptosis and promoted regeneration.
The article authors are Bin Wang (Internal Medicine, Division of Nephrology & Hypertension, University of Utah), Kyungsook Kim (Adjunct Professor, CSTEC@Utah, Molecular Pharmaceutics), Mi Tian (Internal Medicine, Division of Nephrology & Hypertension, University of Utah), Sumako Kameishi (Post Doctoral Researcher, CSTEC@Utah, Molecular Pharmaceutics), Lili Zhuang (Internal Medicine, Division of Nephrology& Hypertension, University of Utah), Teruo Okano (Distinguished Adjunct Professor, CSTEC@Utah, Molecular Pharmaceutics), and Yufeng Huang (Internal Medicine, Division of Nephrology; Hypertension, University of Utah).
Congratulations Drs. Kim, Kameishi, Okano, and to their collaborators!